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Herbs > A - D Herbs > Cinnamon

Use as Part of Your Diet to Help Maintain a Healthy Blood Sugar Level*

Cinnamon, a staple ingredient in apple pie, has remained one of the world's favorite spices throughout recorded history. The evergreen cinnamon tree (Cinnamomum verum), considered to be true cinnamon, is native to Sri Lanka. Chinese cinnamon (Cinnamomum cassia or Cinnamomum aromaticum), the cinnamon most commonly sold in the U.S., goes by the name "Cassia". Usage of cinnamon in Chinese medicine is said to date back over 4,000 years. Mentioned in the Bible, cinnamon was imported to Egypt and Europe from the Far East by 500 B.C. In addition to its value as culinary spice, cinnamon has traditionally been utilized as a folk medicine for colds and minor digestive complaints. True cinnamon and cassia are very similar; cassia has a more pungent flavor. Cassia buds can be found in potpourri and used as a flavoring agent in sweets and beverages.1

Ingredients per Capsule:

Cinnamon bark extract 125 mg
(Cinnamomum cassia auct,)

Excipients: modified cellulose (vegetarian capsule), cellulose, magnesium silicate, silicon dioxide, magnesium steareate.

Suggested Adult Use: Take one capsule two times daily, before or during a meal.

Recent research has revealed that constituents in cinnamon bark called procyanidin Type-A polymers help maintain the body's ability to metabolize glucose in a healthy way.* Best Cinnamon Extract is Cinnulin PF®, a patented, water extract of Cinnamon that contains Type-A polymers. Cinnulin PF® is a registered trademark of Integrity Nutraceuticals International and is manufactured under US Patent # 6,200,569.

HUMAN CLINICAL TRIALS

The effect of cinnamon on glucose and blood lipids levels on people with type 2 diabetes was tested in a recent randomized, placebo-controlled trial. A total of 60 subjects were divided into six groups administered 1, 3, or 6 grams of cinnamon daily, in 500 mg capsules, or equal numbers of placebo capsules.

The cinnamon or placebo capsules were consumed for two periods of 20 days each. Serum glucose, triglyceride, cholesterol, LDL cholesterol and HDL cholesterol were measured after 20 days, 40 days and again at the end of a 20-day wash-out period, during which neither cinnamon nor placebo was consumed.

In all three cinnamon groups, statistically significant reductions in blood glucose levels occurred, with decreases ranging from 18 to 29 percent. Interestingly, glucose levels remained significantly lower after the 20-day wash-out period (60 days from the study start) only in the group that took the lowest cinnamon dose (1 gram daily). The placebo groups showed no significant changes.

Decreases in triglyceride levels ranging from 23 to 30% were observed in all three cinnamon groups after 40 days. When the study ended at 60 days, triglyceride levels remained lower than at the study start in the 1 and 3 gram cinnamon groups, but not in the group taking 6 grams daily. Cholesterol reductions also occurred with the three cinnamon doses, with decreases ranging from 13 to 25% that were maintained at the study end. For LDL, the 3 and 6 gram cinnamon groups showed significant reductions from 10 to 24%, while in the 1 gram cinnamon group, non-significant reductions occurred after 40 days; LDL levels continued to decrease, reaching statistical significance at 60 days. With respect to HDL, significant increases were seen only in the 3 gram cinnamon group after 20 days; non-significant changes occurred in the 1 and 6 gram groups after 40 days.

The overall results of this trial demonstrate that cinnamon exerts a beneficial effect on blood glucose and lipid levels in people with type 2 diabetes, at daily intakes of 1 gram, and that this low dose is equally efficacious as are the higher doses of 3 and 6 grams.10

Scientific References

1. Manniche, L. An Ancient Egyptian Herbal. 1989, Austin , TX : University of Texas Press.

2. Khan A, Bryden NA, Polansky MM, Anderson RA. Insulin potentiating factor and chromium content of selected foods and spices. Biol Trace Elem Res 1990;24(3):183-8.

3. Broadhurst CL, Polansky MM, Anderson R. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J Agric Food Chem 2000;48(3):849-52.

4. Jarvill-Taylor KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll Nutr 2001;20(4):327-36.

5. Nadiv O, Shinitzky M, Manu H, et al. Elevated protein tyrosine phosphatase activity and increased membrane viscosity are associated with impaired activation of the insulin receptor kinase in old rats. Biochem J. 1998;298(Pt 2):443-50.

6. Begum N, Sussman KE, Draznin B. Differential effects of diabetes on adipocyte and liver phosphotyrosine and phsophoserine phosphatase activities. Diabetes 1991;40(12):1620-9.

7. Imparl-Radosevich J, Deas S, Polansky MM, et al. Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling. Horm Res 1998;50:177-182.

8. Qin B, Nagasaki M, Ren M, et al. Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated glucose utilization via enhanced insulin signaling in rats. Diabetes Res Clin Pract 2003;62(3):139-48.

9. Anderson R, Broadhurst CL, Polansky MM, et al. Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity. J Agric Food Chem 2004; 52(1):65-70.

10. Khan A, Safdar S, Muzaffar M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26(12):3215-18.

11. Duke, JA. Handbook of Phytochemical Constituents of GRAS Herbs and Other Economic Plants. 1992. Boca Raton, FL: CRC Press.

12. Botanical Safety Handbook. American Herbal Products Association. McGuffin M, et al., eds. 1997; Boca Raton , FL : CRC Press.

Acting as a biochemical "super-thiamin," it does this through several different cellular mechanisms